Canine Distemper- Adenovirus Type-2 Coronavirus parainfluenza-parvovirus vaccine. Modified live and killed virus. Leptospira Bacterin.  For vaccination of healthy dogs against canine distemper virus, canine infectious hepatitis, canine respiratory infection, canine parainfluenza, canine parvovirus, canine coronavirus and leptospirosis. Vaccinate healthy dogs 6 weeks of age or older 1mL subcutaneously, repeat every 3-4 weeks until 12 weeks old. Annual revaccination is recommended. Do not use on pregnant bitches.