Cosequin plays an important role in maintaining optimal joint function. The superior quality ingredients in this patented formula provide the raw materials that are essential for the synthesis of synovial fluid and the major components of articular cartilage matrix. Each level scoopful of Cosequin Equine Powder (3.3 grams) contains: Glucosamine HCl 99+% 1800 mg Sodium Chondroitin Sulfate 95% Mixed Glycosaminoglycans 5% 600 mg Ascorbate (as Manganese Ascorbate) 104 mg Manganese (as Ascorbate) 16 mg Joints and Articular Cartilage. The performance and mobility of your horse is dramatically affected by how well his joints function. While physical conditioning can strengthen muscles, bones, and tendons, the tremendous forces exerted on the skeletal joints (fetlock, knee, stifle and hock) during training and competition causes wear and tear to the joint cartilage. Articular cartilage is critical to joint utility. Immersed in synovial fluid, articular cartilage provides a smooth, low friction surface between bone ends, and transmits load forces to the underlying bones.