Duramune Max 5 CVK/ 4L. Canine Distemper Adenovirus Type 2 Parainfluenza Parvovirus Vaccine. Modified live and killed virus, Leptospira Bacterin. The Puppy Shot Booster. Vaccinate healthy dogs, 1mL subcutaneously at 6 weeks old; repeat every 2-3 weeks until 12 weeks old. If over 12 weeks old; repeat in 2-3 weeks. Aids in the prevention of disease caused by canine distemper, infectious canine hepatitis,canine coronavirus, canine adenovirus type 2, canine parainfluenza, canine parvovirus, and leptospira. Revaccinate annually. For veterinary use only.