Canine Distemper, Adenovirus Type 2, Parainfluenza, Parvo Modified Live, Leptospira Bacterin. Vaccinate healthy dogs 6 weeks of age with 1mL, intramuscularly or subcutaneously, repeat every 3-4 weeks until 12 weeks old. Give dogs over 12 weeks old 2 doses 3-4 weeks apart. Avoid vaccinating pregnant bitches. Revaccinate annually.